![]() ![]() The application bundles a wide array of features and tools designed to guide you through all the necessary steps of organizing the information and performing detailed statistical analysis. Therefore, you can get started by opening your own file or you can simply start from scratch by choosing one of the projects. The application comes with a user-friendly interface and fine-tuned documentation where you can learn tips and tricks suitable for both beginners and advanced users. Comes with an extensive library of analyses Our results highlight a distinct chemical reprogramming pathway that leads to a shortcut for the generation of human pluripotent stem cells, which represents a powerful strategy for human cell fate manipulation.GraphPad Prism is a robust application packed with a full-featured, comprehensive biostatistics features that aims to assist biologists and researchers in analyzing complex sets of data and generating understandable graphs. ![]() We found that this optimized protocol enabled a more direct reprogramming process by promoting cell proliferation and oxidative phosphorylation metabolic activities at the early stage. Here, by screening for small molecule boosters and systematically optimizing the original condition, we have established a robust, chemically defined reprogramming protocol, which greatly shortens the induction time from ∼50 days to a minimum of 16 days and enables highly reproducible and efficient generation of hCiPSCs from all 17 tested donors. ![]() However, the utility of this chemical approach is currently hampered by slow kinetics. We recently demonstrated the chemical reprogramming of human somatic cells to pluripotent stem cells (hCiPSCs), which provides a robust approach for cell fate manipulation. ![]()
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